主讲人：赵云德

美国加州大学SanDiego分校植物科学系系主任教授、“千人计划”特聘专家、“长江学者”讲座教授

时 间：2019年4月4日10:00-11:30

地 点：上海交通大学闵行校区生物药学楼树华报告厅

赵云德，博士，美国加州大学分校终身教授、中组部“千人计划”特聘专家、南京农业大学“长江学者”讲座教授。1990年于中国科学院上海药物研究所获微生物学硕士学位后赴美留学，在美国密歇根大学获博士学位，毕业后在著名的The Salk Institute进行博士后工作。主要从事生长素在发育过程中的作用机理方面的研究，在植物生长素的合成、修饰、运输和信号转导的分子机理研究领域取得多项突破性成果。以第一作者或通讯作者身份在Science、Cell、Gene and Development、PNAS、Plant Cell等国际著名期刊上发表多篇学术论文篇，包括应邀为Annual Review of Plant Biology等杂志所撰写的综述。文章引用数超过10000次, H指数51。

报告简介：

CRISPR gene editing technologies have revolutionized biology and crop improvement. In this presentation, I will first describe the remaining challenges of gene editing technologies in plants followed by presenting our effort in improving several aspects of CRISPR gene editing technology. I will focus on two main areas of CRISPR technology: Homology-directed DNA repair (HDR) and transgene-free genome editing. HDR has been regarded as the Holy Grail of genome editing in plants and offers unprecedented applications in agriculture. We have developed new strategies that enabled HDR-based gene replacements in plants. Transgene-free is likely a prerequisite to gain regulatory approval of edited crops. My group has pioneered several strategies that accelerate the isolation of transgene-free, gene-edited plants. Our latest technology allows the isolation of edited, transgene-free plants within a single generation, greatly accelerating crop breeding. I will use editing auxin pathways as an example to demonstrate the power of our new technologies in both basic and applied plant biology.